Searchable abstracts of presentations at key conferences in endocrinology

ea0056p1176 | Thyroid cancer | ECE2018

131I-MIBG as a treatment in medullary thyroid carcinoma with distant metastases.

Uriarte Nerea Utrilla , Fernandez Pedro Gonzalez , Figueruelo Alba Esteban , Herrero Marina Nevares , Sandi Javier Santamaria

Introduction and objectives: The strategies for therapy of metastatic medullary thyroid carcinoma (MTC) are limited. Although Tyrosine kinase inhibitors (TKI) seem to be the first-line treatment, we want to explore other possibilities. Metaiodobenzylguanidine (MIBG) is a guanethidine derivative, structurally similar to norepinephrine. It was developed as an imaging agent with 123I radiolabeling. MIBG localizes neuroendocrine tumors including MTC. We are investigatin...